WHAT EXACTLY IS CJC-1295 Gibraltar ?

CJC-1295 gib is a 30 amino synthesized GHRH (anabolic hormones releasing hormone) analog. Its been demonstrated to be highly efficient in increasing thyroid hormone production and IGF-1 without negatively influencing GH secretion pulsatility.

Because of its increased specificity as a GHRH, CJC-1295 gib frequently coupled with Ipamorelin. This peptide stimulates growth hormone production similarly to other peptides in its family, but without the hunger stimulation and rise in cortisone, cholinergic, dopamine, and adrenaline reported with other peptides in its family. In addition, when coupled with Ipamorelin, this peptide has been proven to be very well tolerated.

Pituitary Gland Stimulated


improved high flow and IGF-1 levels, but no rise in prolactin levels

• Enhanced body mass and height as a result of higher protein synthesis

• Muscle Growth Acceleration

• Greater Bone Density

• Increased Immune Function

• Better cognition and memory

• Enhanced Collagen Production

• Enhanced Fat Loss

• Improved cell repair and regeneration

CJC-1295 also enhances slow-wave deep sleep, essential for muscular development, memory retention, and rejuvenation.

CJC 1295 Gibraltar comes in two varieties:

The hypothalamus produces GHRH (growth hormone-releasing hormone). Its pulsatile release from the hypothalamus causes the pituitary gland to produce GH pulsatility. As a result, GHRH has an extremely short half-life (the time necessary to eliminate half of the chemical from the blood). The shorter the half-life, the faster the chemical is eliminated from the body and the less influence it has on the body).

The active portion of GHRH is the first 29 amino acids. They are accessible as a synthetic peptide known as Sermorelin. Sermorelin’s half-life was increased to 30 minutes by additional modification. Thus, it is known as CJC 1295. CJC-1295  further modified by the addition of DAC (Drug Affinity Complex). DAC attaches to albumin, a blood protein, increasing its half-life to 8 days. Thus, it’s known as CJC 1295 + DAC. CJC 1295 can also be synthesized in a non-DAC form, simulating a more realistic physiologic GH increase each night.

Because of the prolonged half-life of the DAC binding to albumin, injections only needed once or twice each week. The lengthy half-life and relatively constant blood level, on the other hand, give a persistent stimulation for pituitary GH production via the GHRH receptor, which is not normal. It can reduce the amplitude of the GH pulse, resulting in less GH tissue activation.


When utilizing a long-acting CJC molecule, it is suggested to take three months off every three to six months to allow the pituitary to recover.’ Sermorelin is used instead of CJC 1295 + DAC throughout the holidays.

The ‘hormone vacations’ may also reduce the likelihood of GH resistance developing. This tolerance, or unresponsiveness, may result from the formation of antibodies which attach to it and inhibit GH, or from a reduction in the number of Growth hormone receptor on organs (down-regulation). However, because no long-term research conducted to elucidate the difficulties, they are theoretical problems.

Injection responses (irritation, erythema, induration, discomfort, itching), headache, diarrhea, vasodilation (flushing, warmth, transitory hypotension), nausea, and stomach discomfort are possible effects of CJC-1295.